Description

3-(2-Trifluoromethyl-Phenyl)-Propionaldehyde is a specialized fluorinated aromatic aldehyde building block. This compound matters for its unique trifluoromethyl group, which imparts enhanced metabolic stability, lipophilicity, and bioavailability to target molecules. It is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in CNS and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the CF3 group improves biological activity.
• Material Science: Serves as a precursor for specialty polymers and liquid crystals that require fluorinated aromatic components.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, Grignard reactions, and reductive amination to introduce the 2-(trifluoromethyl)benzyl moiety.
• Fluorine Chemistry Research: A valuable compound for academic and industrial research exploring the effects of fluorination on chemical and physical properties.

Basic Information

Product Name	3-(2-Trifluoromethyl-Phenyl)-Propionaldehyde
CAS No.	376641-58-6
Molecular Formula	C10H9F3O
Molecular Weight	202.17 g/mol
Synonyms	3-[2-(Trifluoromethyl)phenyl]propanal; 2-(Trifluoromethyl)hydrocinnamaldehyde; 3-(2-Trifluoromethylphenyl)propanal; 3-(2-Trifluoromethylphenyl)propionaldehyde; 2-(Trifluoromethyl)benzylacetaldehyde; (2-Trifluoromethylphenyl)propionaldehyde; 3-(α,α,α-Trifluoro-o-tolyl)propionaldehyde
EINECS	Contact for details

Quality Control

Our 3-(2-Trifluoromethyl-Phenyl)-Propionaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopy (NMR, IR), to ensure high purity and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all specified parameters. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and is sensitive to fluoride/strong alkali. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.