Description

(1,2-Dihydro-1-Oxo-6-Isoquinolinyl)Boronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in its role as a key reagent in Suzuki-Miyaura cross-coupling reactions, enabling the efficient formation of carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the synthesis of complex heterocyclic compounds and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those containing the isoquinoline scaffold for therapeutic applications.
• Suzuki-Miyaura Cross-Coupling Reagent: Used as a versatile coupling partner with aryl or vinyl halides to construct biaryl and other complex molecular architectures under palladium catalysis.
• Agrochemical Research: Employed in the development of new herbicides, fungicides, and insecticides that require specific heterocyclic structures.
• Material Science: Serves as a monomer or functionalization agent in the creation of advanced organic electronic materials and polymers.
• Chemical Biology & Proteomics: Utilized in the design and synthesis of molecular probes and inhibitors for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring high-fidelity boronic acid components.

Basic Information

Product Name	(1,2-Dihydro-1-Oxo-6-Isoquinolinyl)Boronic Acid
CAS No.	376584-82-6
Molecular Formula	C9H8BNO3
Molecular Weight	188.98 g/mol
Synonyms	6-Isoquinolinylboronic Acid, 1,2-Dihydro-1-oxo-; 1-Oxo-1,2-dihydro-6-isoquinolineboronic Acid; (1-Oxo-1,2-dihydroisoquinolin-6-yl)boronic Acid; 6-Borono-1,2-dihydroisoquinolin-1-one; 1,2-Dihydro-1-oxo-6-isoquinolineboronic Acid; (1,2-Dihydro-1-oxoisoquinolin-6-yl)boronic Acid; B-(1,2-Dihydro-1-oxo-6-isoquinolinyl)boronic Acid
EINECS	Contact for details

Quality Control

Our (1,2-Dihydro-1-Oxo-6-Isoquinolinyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.