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2-Benzo[B]Thiophene-2-Boronic Acid Pinacol Ester CAS NO 376584-76-8


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CAS No.:376584-76-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Benzo[B]Thiophene-2-Boronic Acid Pinacol Ester is a high-purity, organoboron building block essential for modern synthetic chemistry. This compound is a critical reagent in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for drug discovery and advanced material development.

Application

  • Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of complex organic molecules, particularly those containing the benzothiophene scaffold.
  • Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs) for various therapeutic areas.
  • Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides.
  • Organic Light-Emitting Diode (OLED) Materials: Employed in the synthesis of advanced organic electronic materials for display and lighting technologies.
  • Ligand and Catalyst Development: Useful for preparing novel ligands and organometallic catalysts for asymmetric synthesis.
  • Polymer Chemistry: Can be incorporated into polymer backbones to modify material properties for specialty plastics and coatings.

Basic Information

Product Name 2-Benzo[B]Thiophene-2-Boronic Acid Pinacol Ester
CAS No. 376584-76-8
Molecular Formula C₁₄H₁₇BO₂S
Molecular Weight 260.16 g/mol
Synonyms 2-(Benzo[b]thiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-(2-Benzo[b]thienyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Benzo[b]thiophene-2-boronic acid pinacol ester; 2-Benzo[b]thienylboronic acid pinacol ester; 2-(Benzo[b]thiophen-2-yl)-1,3,2-dioxaborolane, 4,4,5,5-tetramethyl-; 2-Thianaphthenylboronic Acid Pinacol Ester; 2-BTBP
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Quality Control

Our 2-Benzo[B]Thiophene-2-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat and incompatible materials.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥97.0%
Water Content (KF) ≤0.5%
Residue on Ignition ≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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