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Pyrazole-3-Boronic Acid CAS NO 376584-63-3


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CAS No.:376584-63-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Pyrazole-3-Boronic Acid is a high-value boronic acid derivative and a key synthetic building block in modern organic chemistry. This compound is essential for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for the development of novel active ingredients and functional molecules.

Application

  • Pharmaceutical Intermediate: A crucial building block for synthesizing pyrazole-containing drug candidates, including kinase inhibitors and other biologically active molecules.
  • Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that incorporate the pyrazole heterocycle.
  • Material Science Research: Serves as a precursor for creating organic electronic materials, metal-organic frameworks (MOFs), and functional polymers via cross-coupling.
  • Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and tags for studying biological processes and diagnostics.
  • Catalyst Ligand Synthesis: Used to prepare novel bidentate or polydentate ligands for transition metal catalysis.
  • Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects at various scales.

Basic Information

Product Name Pyrazole-3-Boronic Acid
CAS No. 376584-63-3
Molecular Formula C3H5BN2O2
Molecular Weight 111.89 g/mol
Synonyms 1H-Pyrazole-3-boronic acid; 3-Pyrazoleboronic acid; (1H-Pyrazol-3-yl)boronic acid; 3-Boronopyrazole; Pyrazol-3-ylboronic acid; 3-Pyrazolylboronic Acid; 1H-Pyrazol-3-ylboronic Acid; Pyrazole-3-yl-Boronic Acid
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Quality Control

Our Pyrazole-3-Boronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of our global customer base in advanced synthetic chemistry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, keeping the material under an inert atmosphere (e.g., nitrogen or argon) is recommended to maintain stability. Recommended storage temperature is 2-8°C.

Specification

Item Specification
Appearance White to off-white powder or crystalline solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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