Description

Quinoline-6-Boronic Acid is a versatile and high-value boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its primary value lies in enabling the efficient construction of complex molecules through reliable cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and scalable synthetic pathways. Its specific structure makes it a preferred reagent for introducing the quinoline moiety into target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the quinoline scaffold for enhanced biological activity.
• Material Science Research: Employed in the creation of organic light-emitting diodes (OLEDs), conductive polymers, and metal-organic frameworks (MOFs) due to its electron-deficient aromatic system.
• Suzuki-Miyaura Cross-Coupling: Functions as a pivotal boronic acid partner in Pd-catalyzed cross-coupling reactions to form biaryl and heterobiaryl structures.
• Chemical Biology & Proteomics: Utilized as a handle for bioconjugation and in the development of chemical probes and enzyme inhibitors.
• Ligand Synthesis: Serves as a starting material for constructing sophisticated chiral and achiral ligands used in catalysis.

Basic Information

Item	Detail
Product Name	Quinoline-6-Boronic Acid
CAS No.	376581-24-7
Molecular Formula	C9H8BNO2
Molecular Weight	173.98 g/mol
Synonyms	6-Quinolineboronic Acid; (6-Quinolinyl)boronic Acid; Quinolin-6-ylboronic Acid; B-(6-Quinolyl)boronic Acid; 6-Boronquinoline; Quinoline 6-Boronic Acid Pinacol Ester (precursor); 6-Quinolylboronic Acid
EINECS	Contact for details

Quality Control

Every batch of Quinoline-6-Boronic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and other relevant techniques is supplied with each shipment. Our quality commitment aligns with cGMP principles for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.