Description

1,2,3,6-Tetrahydropyridine-4-Yl-Boronic Acid Pinacol Ester is a high-value organoboron building block used in advanced organic synthesis. This compound is critical for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug candidates, particularly those containing nitrogen heterocycles.
• Suzuki-Miyaura Cross-Coupling: Enables the formation of carbon-carbon bonds between the tetrahydropyridine moiety and aryl/heteroaryl halides under palladium catalysis.
• Agrochemical Research: Used in the development of new pesticides and herbicides requiring specific heterocyclic architectures.
• Material Science: Potential precursor for creating functionalized polymers or organic electronic materials with tailored properties.
• Chemical Biology: Useful as a probe or linker in bioconjugation chemistry and the development of chemical tools.
• Academic & Contract Research: Essential reagent for methodological development and library synthesis in academic and CRO laboratories.

Basic Information

Product Name	1,2,3,6-Tetrahydropyridine-4-Yl-Boronic Acid Pinacol Ester
CAS No.	375853-82-0
Molecular Formula	C11H20BNO2
Molecular Weight	209.09 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,6-tetrahydropyridine; 1,2,3,6-Tetrahydro-4-pyridineboronic acid pinacol ester; 4-(Pinacolboranyl)-1,2,3,6-tetrahydropyridine; 4-Borono-1,2,3,6-tetrahydropyridine, pinacol ester; 1,2,3,6-Tetrahydropyridin-4-ylboronic acid pinacol ester; 4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-3,6-dihydro-2H-pyridine
EINECS	Contact for details

Quality Control

Our 1,2,3,6-Tetrahydropyridine-4-Yl-Boronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific research or cGMP requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry place. This material is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid or crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Typical: 97-99%)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.