Description

3-(4-Chloro-1-Naphthyl)-3-Oxopropanenitrile is a specialized organic building block featuring a naphthyl ketone core functionalized with a nitrile group. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working on novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and organic electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Dye & Pigment Intermediate: Acts as a building block for creating novel chromophores and functional dyes due to its conjugated naphthalene system.

Basic Information

Product Name	3-(4-Chloro-1-Naphthyl)-3-Oxopropanenitrile
CAS No.	374926-12-2
Molecular Formula	C₁₃H₈ClNO
Molecular Weight	229.66 g/mol
Synonyms	4-Chloro-1-naphthyl cyanomethyl ketone; 3-Oxo-3-(4-chloro-1-naphthyl)propanenitrile; 4'-Chloro-1'-naphthylacetonitrile ketone; 1-(4-Chloronaphthalen-1-yl)-2-cyanoethan-1-one; (4-Chloro-1-naphthoyl)acetonitrile; 2-Cyano-1-(4-chloro-1-naphthyl)ethanone; Propanenitrile, 3-(4-chloro-1-naphthyl)-3-oxo-
EINECS	Contact for details

Quality Control

Our 3-(4-Chloro-1-Naphthyl)-3-Oxopropanenitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), residual solvents, and other critical parameters is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.