Description

4-Butyl-8-Methyl-7-Phenacyloxychromen-2-One is a specialized synthetic coumarin derivative with a unique phenacyloxy substitution pattern. This compound serves as a critical advanced intermediate in the synthesis of complex organic molecules, offering a versatile scaffold for pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development teams in the fine chemical, pharmaceutical, and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in therapeutic areas requiring complex heterocyclic frameworks.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the bioactivity of the coumarin core.
• Organic Synthesis: Acts as a versatile precursor for constructing more complex molecular architectures in academic and industrial research laboratories.
• Material Science: Potential intermediate for the synthesis of organic light-emitting diodes (OLEDs) or fluorescent markers due to the chromen-2-one structure.
• Chemical Biology: Useful as a probe or tag in biochemical research to study enzyme interactions or cellular processes.

Basic Information

Product Name	4-Butyl-8-Methyl-7-Phenacyloxychromen-2-One
CAS No.	374767-20-1
Molecular Formula	C24H24O4
Molecular Weight	376.45 g/mol
Synonyms	7-(2-Oxo-2-phenylethoxy)-4-butyl-8-methyl-2H-chromen-2-one; 4-Butyl-8-methyl-7-phenacyloxycoumarin; 4-n-Butyl-8-methyl-7-phenacyloxy-2H-1-benzopyran-2-one; 7-Phenacyloxy-4-butyl-8-methylcoumarin; Phenacyl Ether of 4-Butyl-8-methyl-7-hydroxycoumarin; 374767-20-1; 4-Butyl-8-methyl-7-(2-oxo-2-phenylethoxy)chromen-2-one
EINECS	Contact for details

Quality Control

Our production of 4-Butyl-8-Methyl-7-Phenacyloxychromen-2-One adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Every lot is fully characterized and tested against comprehensive specifications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to handle under an inert atmosphere for long-term storage and to minimize headspace in opened containers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.