Description

2-n-Boc-Amino-6-Ethoxycarbonylpyridine-4-Boronic Acid Pinacol Ester is a high-value, multifunctional building block in modern organic synthesis, specifically designed for cross-coupling reactions. Its core value lies in enabling the precise construction of complex heterocyclic scaffolds critical for pharmaceutical and agrochemical discovery. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-purity intermediates for Suzuki-Miyaura couplings and other palladium-catalyzed transformations.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing functionalized pyridine cores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific heterocyclic structures.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic ester coupling partner for the formation of carbon-carbon bonds with aryl/heteroaryl halides.
• Ligand and Catalyst Development: A precursor for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those for OLEDs or conductive polymers, where tailored pyridine derivatives are needed.
• Chemical Biology Probes: Useful for constructing molecular probes and tags for studying biological systems and target engagement.

Basic Information

Item	Detail
Product Name	2-n-Boc-Amino-6-Ethoxycarbonylpyridine-4-Boronic Acid Pinacol Ester
CAS No.	374671-12-2
Molecular Formula	C19H27BN2O6
Molecular Weight	390.24 g/mol
Synonyms	2-((tert-Butoxycarbonyl)amino)-6-(ethoxycarbonyl)pyridine-4-boronic acid pinacol ester; 2-(Boc-amino)-6-(ethoxycarbonyl)pyridine-4-boronic acid pinacol ester; 4-Borono-2-((tert-butoxycarbonyl)amino)-6-(ethoxycarbonyl)pyridine pinacol ester; 2-N-Boc-amino-6-ethoxycarbonylpyridine-4-boronic acid pinacol ester; 6-Ethoxycarbonyl-2-(Boc-amino)pyridine-4-boronic acid pinacol ester; tert-Butyl (6-(ethoxycarbonyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)carbamate
EINECS	Contact for details

Quality Control

Our 2-n-Boc-Amino-6-Ethoxycarbonylpyridine-4-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.