Description

4-Chloro-6-Thiophen-2-Yl-Pyrimidine is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential kinase inhibitors and other small-molecule drug candidates.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science Precursor: Serves as a monomer or functional unit in the design of organic electronic materials and conductive polymers.
• Chemical Biology Probe: Utilized in the creation of tool compounds for studying biological pathways and target validation.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic projects.
• Academic Research: A valuable reagent for methodological studies in heterocyclic and cross-coupling chemistry.

Basic Information

Product Name	4-Chloro-6-Thiophen-2-Yl-Pyrimidine
CAS No.	374554-75-3
Molecular Formula	C8H5ClN2S
Molecular Weight	196.66 g/mol
Synonyms	4-Chloro-6-(thiophen-2-yl)pyrimidine; 6-(2-Thienyl)-4-chloropyrimidine; 4-Chloro-6-(2-thienyl)pyrimidine; 4-Chloro-6-thiophen-2-ylpyrimidine; 2-(4-Chloropyrimidin-6-yl)thiophene; Pyrimidine, 4-chloro-6-(2-thienyl)-; 374554-75-3
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-Thiophen-2-Yl-Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our standard material meets a typical purity specification of ≥97% (HPLC), with higher grades available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.