Description

3-Bromobenzeneboronic Acid n-Methyldiethanolamine Ester is a specialized organoboron reagent, a protected boronic acid derivative designed for enhanced stability and handling. This compound is a critical intermediate in modern synthetic chemistry, particularly in cross-coupling reactions like the Suzuki-Miyaura reaction, where it facilitates the formation of carbon-carbon bonds with high efficiency and selectivity. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, enabling the introduction of the 3-bromophenyl moiety.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific aryl-bromide functionalities.
• Material Science: Serves as a monomer or precursor in the creation of organic electronic materials, such as polymers for OLEDs or conductive films.
• Suzuki-Miyaura Cross-Coupling: The protected boronic ester form offers improved stability against protodeboronation, making it a reliable partner for palladium-catalyzed coupling with various aryl/vinyl halides.
• Chemical Research & Development: An essential reagent for method development, library synthesis, and exploring new synthetic pathways in academic and industrial R&D laboratories.
• Ligand and Catalyst Preparation: Can be used to synthesize sophisticated ligands for catalysis or as a component in metal-organic frameworks (MOFs).

Basic Information

Item	Detail
Product Name	3-Bromobenzeneboronic Acid n-Methyldiethanolamine Ester
CAS No.	374538-00-8
Molecular Formula	C11H17BBrNO2
Molecular Weight	286.98 g/mol
Synonyms	B-(3-Bromophenyl)-N-methyl-2,2'-iminodiethanolboronate; 3-Bromophenylboronic Acid N-methyldiethanolamine Ester; (3-Bromophenyl)boronic Acid MDEA Ester; N-Methyldiethanolamine 3-Bromobenzeneboronate; Boronic Acid B-(3-Bromophenyl)-, N-Methyldiethanolamine Ester; 374538-00-8; 3-Bromophenylboronic Acid MDEA Complex
EINECS	Contact for details

Quality Control

Our 3-Bromobenzeneboronic Acid n-Methyldiethanolamine Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR (1H, 13C, 11B), HPLC, and elemental analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.