Description

3-Isopropylbenzeneboronic Acid Ethylene Glycol Ester is a protected boronic acid derivative, a crucial intermediate in modern synthetic organic chemistry. This compound is valued for its enhanced stability compared to its free boronic acid counterpart, facilitating handling and storage in demanding industrial processes. It is primarily utilized by researchers and manufacturers in the pharmaceutical and agrochemical sectors for advanced cross-coupling reactions, such as the Suzuki-Miyaura reaction, to construct complex biaryl structures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that require specific biaryl or substituted phenyl motifs.
• Material Science Research: Serves as a monomer or precursor in the development of organic electronic materials, including polymers for OLEDs and conductive films.
• Ligand and Catalyst Development: Employed in the preparation of novel boron-containing ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Library Production: Utilized in combinatorial chemistry and high-throughput screening for the generation of diverse compound libraries in drug discovery.
• Academic & Industrial R&D: A versatile reagent for methodological development in organic synthesis laboratories worldwide.

Basic Information

Product Name	3-Isopropylbenzeneboronic Acid Ethylene Glycol Ester
CAS No.	374537-96-9
Molecular Formula	C11H15BO2
Molecular Weight	190.05 g/mol
Synonyms	(3-Isopropylphenyl)boronic acid ethylene glycol ester; 3-Isopropylbenzeneboronic acid cyclic ethylene ester; 5-Isopropyl-2-phenyl-1,3,2-dioxaborolane; 3-Isopropylphenylboronic acid pinacol ester (common misnomer, note structural difference); m-Isopropylbenzeneboronic acid ethylene glycol ester; B-(3-Isopropylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (incorrect but frequently searched); Boronic acid, B-(3-isopropylphenyl)-, cyclic ethylene ester
EINECS	Contact for details

Quality Control

Our 3-Isopropylbenzeneboronic Acid Ethylene Glycol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with stringent industry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive). For long-term storage, consider using desiccants or storing under an inert atmosphere to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.