Description

Ethyl (2E)-5-[4-(Acetyloxy)Phenyl]-7-Methyl-3-Oxo-2-[4-(Propan-2-Yl)Benzylidene]-2,3-Dihydro-5H-[1,3]Thiazolo[3,2-A]Pyrimidine-6-Carboxylate is a high-purity, complex heterocyclic organic compound with significant potential in advanced chemical synthesis. This molecule serves as a critical building block or intermediate for developing novel active ingredients in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working in medicinal chemistry, crop protection, and specialty chemical sectors who require reliable, high-quality intermediates for their innovative projects.

Application

This specialized chemical intermediate is designed for research and development applications where precise molecular architecture is paramount. Key application areas include:

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly those targeting specific biological pathways.
• Agrochemical Research: Used as a building block for synthesizing novel active ingredients for crop protection products, such as herbicides or fungicides.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization processes due to its complex fused-ring system.
• Chemical Biology: Potential use as a probe or tool compound in biochemical assays to study enzyme inhibition or receptor binding.
• Organic Synthesis: Acts as a versatile intermediate for synthesizing more complex heterocyclic compounds in academic and industrial research settings.
• Material Science Research: Investigated for potential use in the development of organic electronic materials or advanced polymers.

Basic Information

Product Name	Ethyl (2E)-5-[4-(Acetyloxy)Phenyl]-7-Methyl-3-Oxo-2-[4-(Propan-2-Yl)Benzylidene]-2,3-Dihydro-5H-[1,3]Thiazolo[3,2-A]Pyrimidine-6-Carboxylate
CAS No.	374087-11-3
Molecular Formula	C30H28N2O5S
Molecular Weight	528.62 g/mol
Synonyms	Ethyl 5-(4-acetoxyphenyl)-7-methyl-3-oxo-2-[(4-isopropylphenyl)methylene]-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate; 2-[(4-Isopropylbenzylidene)]-ethyl 5-(4-acetoxyphenyl)-7-methyl-3-oxo-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate; Ethyl 2-[(4-isopropylphenyl)methylene]-5-(4-acetyloxyphenyl)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate; (2E)-Ethyl 5-[4-(acetyloxy)phenyl]-7-methyl-3-oxo-2-[(4-propan-2-yl)benzylidene]-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate; CAS 374087-11-3; Thiazolopyrimidine derivative 374087-11-3
EINECS	Contact for details

Quality Control

Our production of Ethyl (2E)-5-[4-(Acetyloxy)Phenyl]-7-Methyl-3-Oxo-2-[4-(Propan-2-Yl)Benzylidene]-2,3-Dihydro-5H-[1,3]Thiazolo[3,2-A]Pyrimidine-6-Carboxylate adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your research. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) documenting identity, purity, and all relevant specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.