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Diacetato{(S)-(-)-2,2'-Bis[Di(3,5-Xylyl)Phosphino]-1,1'-Binaphthyl}Ruthenium(Ii) CAS NO 374067-49-9


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CAS No.:374067-49-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Diacetato{(S)-(-)-2,2'-Bis[Di(3,5-Xylyl)Phosphino]-1,1'-Binaphthyl}Ruthenium(Ii) is a highly specialized, chiral ruthenium complex designed for asymmetric catalysis. This compound matters because it serves as a precise and efficient catalyst for enantioselective hydrogenation and other critical synthetic transformations, enabling the production of single-isomer intermediates. It is primarily needed by pharmaceutical, agrochemical, and advanced fine chemical manufacturers for the development of chiral active ingredients.

Application

  • Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of prochiral olefins, ketones, and imines in pharmaceutical intermediate synthesis.
  • Chiral Ligand Precursor: The (S)-DTBM-SEGPHOS ligand framework is integral to the complex's activity, making it valuable for developing other catalytic systems.
  • Pharmaceutical Manufacturing: Synthesis of chiral active pharmaceutical ingredients (APIs) requiring high enantiomeric excess (ee).
  • Agrochemical Production: Creation of enantiomerically pure herbicides, fungicides, and plant growth regulators.
  • Fine Chemical Synthesis: Production of specialty chemicals, flavors, and fragrances where stereochemistry is critical.
  • Academic & Industrial R&D: Used in process development and research into new catalytic methodologies.

Basic Information

Item Details
Product Name Diacetato{(S)-(-)-2,2'-Bis[Di(3,5-Xylyl)Phosphino]-1,1'-Binaphthyl}Ruthenium(Ii)
CAS No. 374067-49-9
Molecular Formula C70H66O4P2Ru
Molecular Weight 1124.25 g/mol
Synonyms [Ru(OAc)2((S)-DTBM-SEGPHOS)]; Ruthenium(II) (S)-DTBM-SEGPHOS diacetate; (S)-(-)-2,2'-Bis[Di(3,5-xylyl)phosphino]-1,1'-binaphthyl Ruthenium(II) Diacetate; (S)-DTBM-SEGPHOS Ru diacetate; Ru(OAc)2(S)-DTBM-SEGPHOS; (S)-DTBM-SEGPHOS-Ru(OAc)2; (S)-5,5'-Bis[di(3,5-dimethylphenyl)phosphino]-4,4'-bi-1,3-benzodioxole Ruthenium(II) Diacetate; Ru-DTBM-SEGPHOS(OAc)2
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Quality Control

Our Diacetato{(S)-(-)-2,2'-Bis[Di(3,5-Xylyl)Phosphino]-1,1'-Binaphthyl}Ruthenium(Ii) is produced under strict quality-controlled conditions to ensure batch-to-batch consistency and high catalytic performance. Each lot undergoes comprehensive analysis, including HPLC for purity and chiral assay, to confirm identity and activity. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific GMP or ISO 9001 requirements for advanced manufacturing.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store under an inert atmosphere (argon or nitrogen) at 2-8°C. The product is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or ambient light should be avoided to maintain catalytic efficacy.

Specification

Item Specification
Appearance Orange to red-brown crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Chiral Purity (HPLC) ≥ 99.0% ee
Ruthenium Content 8.5 - 9.5%
Solubility Soluble in dichloromethane, toluene; slightly soluble in alcohols

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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