Description

2,4-Difluoro-3-Methoxy Acetophenone is a high-purity fluorinated aromatic ketone building block of significant importance in advanced organic synthesis. Its value lies in its unique substitution pattern, which makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing active pharmaceutical ingredients (APIs), particularly those containing difluoromethoxy or related pharmacophores.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the fluorine atoms enhance biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials due to its aromatic and fluorinated structure.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in chemical manufacturing.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2,4-Difluoro-3-Methoxy Acetophenone
CAS No.	373603-19-1
Molecular Formula	C9H8F2O2
Molecular Weight	186.16 g/mol
Synonyms	1-(2,4-Difluoro-3-methoxyphenyl)ethan-1-one; 2',4'-Difluoro-3'-methoxyacetophenone; 3-Methoxy-2,4-difluoroacetophenone; 2,4-Difluoro-3-methoxyacetophenone; Acetophenone, 2,4-difluoro-3-methoxy-; Ethanone, 1-(2,4-difluoro-3-methoxyphenyl)-
EINECS	Contact for details

Quality Control

Our 2,4-Difluoro-3-Methoxy Acetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance in regulated applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.