Description

(5Z)-5-[(3-Methylthiophen-2-Yl)Methylidene]-2-(Piperidin-1-Yl)-1,3-Thiazol-4(5H)-One is a high-value, structurally complex heterocyclic compound featuring a thiazolone core fused with methylthiophene and piperidine moieties. This unique molecular architecture makes it a critical advanced pharmaceutical intermediate and a versatile scaffold for medicinal chemistry research. It is primarily sought after by R&D and production teams in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, or inflammatory conditions.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis to discover new bioactive molecules.
• Agrochemical Research: Employed in the development of new fungicides, herbicides, or insecticides due to its heterocyclic structure.
• Chemical Biology Probe: Utilized as a tool compound to study specific biological pathways or protein functions in academic and industrial research settings.
• Organic Synthesis: Acts as a sophisticated reagent or precursor for synthesizing other complex heterocyclic compounds in fine chemical production.

Basic Information

Product Name	(5Z)-5-[(3-Methylthiophen-2-Yl)Methylidene]-2-(Piperidin-1-Yl)-1,3-Thiazol-4(5H)-One
CAS No.	372972-25-3
Molecular Formula	C14H16N2OS2
Molecular Weight	292.42 g/mol
Synonyms	5-[(3-Methyl-2-thienyl)methylene]-2-(1-piperidinyl)-4H-thiazol-4-one; (5Z)-5-[(3-Methylthiophen-2-yl)methylidene]-2-(piperidin-1-yl)-1,3-thiazol-4(5H)-one; 2-Piperidin-1-yl-5-[(3-methylthiophen-2-yl)methylene]thiazol-4-one; 4H-Thiazol-4-one, 5-[(3-methyl-2-thienyl)methylene]-2-(1-piperidinyl)-; Thiazolone derivative CAS 372972-25-3
EINECS	Contact for details

Quality Control

Our production of (5Z)-5-[(3-Methylthiophen-2-Yl)Methylidene]-2-(Piperidin-1-Yl)-1,3-Thiazol-4(5H)-One adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure consistent high-grade material suitable for sensitive R&D and scale-up processes. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.