Description

Methyl 3-(3-Bromophenyl)-4-Nitrobutanoate is a specialized organic building block featuring a bromophenyl group and a nitrobutanoate ester functionality. This compound matters for its role as a key synthetic intermediate in the development of complex, high-value molecules, particularly in pharmaceutical research and fine chemical synthesis. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders or inflammatory pathways.
• Agrochemical Synthesis: Used in research and development for creating novel herbicides, fungicides, or plant growth regulators that require a halogenated aromatic core.
• Organic Synthesis Building Block: Serves as a versatile substrate for various organic transformations, including palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) facilitated by the bromine atom, and reduction or functionalization of the nitro group.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, or organic electronic materials where the specific steric and electronic properties of the molecule are advantageous.
• Chemical Biology Probe Development: Utilized as a scaffold for creating molecular probes to study enzyme function or cellular processes, leveraging its modifiable functional groups.

Basic Information

Product Name	Methyl 3-(3-Bromophenyl)-4-Nitrobutanoate
CAS No.	372944-86-0
Molecular Formula	C11H12BrNO4
Molecular Weight	302.12 g/mol
Synonyms	Methyl 3-(3-bromophenyl)-4-nitrobutyrate; 4-Nitro-3-(3-bromophenyl)butyric Acid Methyl Ester; Butanoic acid, 3-(3-bromophenyl)-4-nitro-, methyl ester; Methyl 4-nitro-3-(3-bromophenyl)butanoate; 3-(3-Bromophenyl)-4-nitrobutyric acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-(3-Bromophenyl)-4-Nitrobutanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or after opening to maintain purity. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.