Description

(Tetrahydro-Thiopyran-4-Yl)-Acetaldehyde is a versatile and valuable aldehyde-functionalized heterocyclic building block. This compound matters as a key chiral intermediate for synthesizing complex molecules, particularly in the pharmaceutical sector where its structure is integral to developing active pharmaceutical ingredients (APIs). It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel sulfur-containing scaffolds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS) and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require specific sulfur heterocycles for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new chemical spaces and reaction methodologies involving sulfur chemistry.
• Flavor & Fragrance Chemistry: Potential use as an intermediate for synthesizing sulfur-containing aroma chemicals, though typically at high purity grades.
• Material Science Precursor: Can be utilized in the development of advanced polymers and functional materials with specific chemical functionalities.

Basic Information

Product Name	(Tetrahydro-Thiopyran-4-Yl)-Acetaldehyde
CAS No.	372159-78-9
Molecular Formula	C7H12OS
Molecular Weight	144.23 g/mol
Synonyms	4-Thianeacetaldehyde, tetrahydro-; Tetrahydro-2H-thiopyran-4-acetaldehyde; 4-(2-Oxoethyl)tetrahydro-2H-thiopyran; 2-(Tetrahydro-2H-thiopyran-4-yl)acetaldehyde; (Tetrahydro-2H-thiopyran-4-yl)acetaldehyde; (THP-4-yl)acetaldehyde; 4-Thiacyclohexaneacetaldehyde
EINECS	Contact for details

Quality Control

Our (Tetrahydro-Thiopyran-4-Yl)-Acetaldehyde is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment. We can supply material compliant with cGMP standards for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture ingress and oxidation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.