Description

2-Bromo-4-(Bromomethyl)-1-(Trifluoromethyl)Benzene is a versatile and highly functionalized aromatic building block. This compound is valued for its dual reactive sites, the bromomethyl and bromo substituents, which allow for sequential and selective functionalization in complex organic syntheses. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing trifluoromethyl groups for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the benzene scaffold provides a core for bioactive molecules.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and polymers due to its halogenated and fluorinated structure.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological systems and drug-target interactions.
• Custom Synthesis & Scale-up: A critical building block for contract research and manufacturing organizations (CROs/CMOs) engaged in custom synthesis projects from milligram to kilogram scale.

Basic Information

Product Name	2-Bromo-4-(Bromomethyl)-1-(Trifluoromethyl)Benzene
CAS No.	372120-77-9
Molecular Formula	C8H5Br2F3
Molecular Weight	317.93 g/mol
Synonyms	1-Bromo-2-(bromomethyl)-5-(trifluoromethyl)benzene; 2-Bromo-α-bromo-α,α,α-trifluoro-p-xylene; 4-Bromomethyl-2-bromo-α,α,α-trifluorotoluene; 2-Bromo-4-(bromomethyl)benzotrifluoride; α,α,α-Trifluoro-2,4-dibromotoluene; 2,4-Dibromo-α,α,α-trifluorotoluene; 2-Bromo-4-bromomethyl-1-trifluoromethylbenzene
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-(Bromomethyl)-1-(Trifluoromethyl)Benzene is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.