Description

Cyclobutanecarboxaldehyde, 1-(Trifluoromethyl)- (9Ci) CAS NO 371917-31-6 is a specialized fluorinated aldehyde building block featuring a cyclobutane ring. This compound is valued for its unique structural motif, which introduces steric and electronic effects critical for modulating the properties of target molecules in advanced synthesis. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides with improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring a functionalized cyclobutane core.

Basic Information

Product Name	Cyclobutanecarboxaldehyde, 1-(Trifluoromethyl)- (9Ci)
CAS No.	371917-31-6
Molecular Formula	C6H7F3O
Molecular Weight	152.11 g/mol
Synonyms	1-(Trifluoromethyl)cyclobutanecarboxaldehyde; 1-(Trifluoromethyl)cyclobutane-1-carbaldehyde; Cyclobutanecarboxaldehyde, 1-(trifluoromethyl)-; (1-(Trifluoromethyl)cyclobutyl)methanal; 371917-31-6; 1-Trifluoromethyl-cyclobutanecarbaldehyde
EINECS	Contact for details

Quality Control

Our Cyclobutanecarboxaldehyde, 1-(Trifluoromethyl)- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, well-ventilated area at 2-8°C for long-term stability. This material is easily oxidized and light-sensitive. Allow the container to reach ambient temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.