Description

5-Bromo-2,3-Dihydro-2,2-Dimethyl-1H-Inden-1-Ol is a specialized brominated indanol derivative that serves as a critical chiral building block and synthetic intermediate in advanced organic synthesis. Its unique sterically hindered structure and bromine substituent make it valuable for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs). This high-purity intermediate is essential for research and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce specific stereochemistry and functional groups into target molecules.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• Agrochemical Synthesis: Building block for developing advanced pesticides and herbicides, leveraging its halogenated indane core.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands for asymmetric catalysis and transition metal complexes.
• Material Science Research: Intermediate for synthesizing organic semiconductors, liquid crystals, and other functional organic materials.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry programs.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	5-Bromo-2,3-Dihydro-2,2-Dimethyl-1H-Inden-1-Ol
CAS No.	371251-54-6
Molecular Formula	C11H13BrO
Molecular Weight	241.13 g/mol
Synonyms	5-Bromo-2,2-dimethyl-2,3-dihydro-1H-inden-1-ol; 5-Bromo-2,2-dimethylindan-1-ol; 1H-Inden-1-ol, 5-bromo-2,3-dihydro-2,2-dimethyl-; (5-Bromo-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)oxidanyl; 5-Bromo-2,2-dimethylindane-1-ol
EINECS	Contact for details

Quality Control

Our 5-Bromo-2,3-Dihydro-2,2-Dimethyl-1H-Inden-1-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles. We support custom synthesis and can tailor specifications to meet specific project requirements, including cGMP standards for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or opaque to prevent degradation. For long-term storage, consider an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee (Typical)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.