Description

2-(3-Fluorophenyl)-1-(4-Fluorophenyl)Ethanone is a high-purity, diaryl ketone building block of significant interest in advanced organic synthesis. Its precise structure, featuring two distinct fluorophenyl rings, makes it a critical intermediate for developing novel pharmaceutical compounds and functional materials. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to incorporate fluorinated aromatic motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology drug candidates.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides where the fluorinated aromatic structure enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic electronic materials, contributing to improved charge transport and thermal stability.
• Polymer Chemistry: Employed in the synthesis of specialty polymers and resins, where the ketone functionality allows for further polymerization or cross-linking reactions.
• Academic & Industrial R&D: A valuable reagent for methodological studies in cross-coupling reactions and fluorine chemistry within research laboratories.
• Fine Chemical Production: Utilized in the multi-step synthesis of complex fluorinated fine chemicals and dyes.

Basic Information

Product Name	2-(3-Fluorophenyl)-1-(4-Fluorophenyl)Ethanone
CAS No.	370874-66-1
Molecular Formula	C14H10F2O
Molecular Weight	232.23 g/mol
Synonyms	1-(4-Fluorophenyl)-2-(3-fluorophenyl)ethanone; 3',4'-Difluorochalcone; 2-(3-Fluorophenyl)-1-(4-fluorophenyl)ethan-1-one; 3-Fluoro-4'-fluorochalcone; (3-Fluorophenyl)(4-fluorophenyl)methanone (common misnomer); 370874-66-1; 2-(3-Fluorophenyl)-1-(4-fluorophenyl)ethanone
EINECS	Contact for details

Quality Control

Our 2-(3-Fluorophenyl)-1-(4-Fluorophenyl)Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.