Description

Ethanone, 1-(3-Ethynyl-4-Hydroxyphenyl)- (9Ci) is a specialized aromatic ketone building block featuring both a phenolic hydroxyl group and an ethynyl moiety, making it a versatile intermediate for advanced organic synthesis. This compound is valued for its ability to participate in click chemistry reactions, such as copper-catalyzed azide-alkyne cycloaddition (CuAAC), enabling the construction of complex molecular architectures. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for constructing drug candidates, particularly those requiring phenolic or alkyne functional groups for further derivatization.
• Click Chemistry Reagent: Serves as a critical alkyne component in Huisgen cycloaddition reactions to create triazole linkages for bioconjugation and polymer chemistry.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators that leverage its unique aromatic backbone.
• Material Science: Employed in the development of advanced polymers, dendrimers, and metal-organic frameworks (MOFs) where precise molecular assembly is required.
• Chemical Biology Probes: Facilitates the labeling and study of biological systems through its reactive alkyne handle for tagging biomolecules.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and catalysis research.

Basic Information

Product Name	Ethanone, 1-(3-Ethynyl-4-Hydroxyphenyl)- (9Ci)
CAS No.	370565-08-5
Molecular Formula	C10H8O2
Molecular Weight	160.17 g/mol
Synonyms	1-(3-Ethynyl-4-hydroxyphenyl)ethanone; 3'-Ethynyl-4'-hydroxyacetophenone; 4'-Hydroxy-3'-ethynylacetophenone; 1-(4-Hydroxy-3-ethynylphenyl)ethan-1-one; 3-Ethynyl-4-hydroxyacetophenone; 4-Hydroxy-3-ethynylacetophenone; Acetophenone, 3'-ethynyl-4'-hydroxy-
EINECS	Contact for details

Quality Control

Our production of Ethanone, 1-(3-Ethynyl-4-Hydroxyphenyl)- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized using advanced analytical techniques, including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.