Description

1,2,4-Tribromo-5-Iodobenzene is a high-purity halogenated aromatic building block of significant interest in advanced organic synthesis. Its unique substitution pattern makes it a valuable precursor for constructing complex molecular architectures, particularly in materials science and pharmaceutical research. This compound is essential for researchers and process chemists in the agrochemical, pharmaceutical, and specialty chemical industries who require reliable, high-quality intermediates for coupling reactions and functional material development.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring halogenated aromatic cores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and pesticides where its halogen atoms provide specific bioactivity and stability.
• Material Science Research: Acts as a monomer or precursor for the synthesis of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the presence of both bromine and iodine leaving groups.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands and organocatalysts for asymmetric synthesis.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical testing and method development in quality control laboratories.

Basic Information

Product Name	1,2,4-Tribromo-5-Iodobenzene
CAS No.	366496-32-4
Molecular Formula	C6H2Br3I
Molecular Weight	470.70 g/mol
Synonyms	5-Iodo-1,2,4-tribromobenzene; Benzene, 1,2,4-tribromo-5-iodo-; 1,2,4-Tribromo-5-iodobenzol; Tribromoiodobenzene (mixed isomers); 366496-32-4 (CAS)
EINECS	Contact for details

Quality Control

Our 1,2,4-Tribromo-5-Iodobenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.