Description

2-(3-Methoxy-5-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in enabling efficient and selective cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds, widely used in pharmaceutical intermediate synthesis.
• Pharmaceutical Research & Development: Serves as a versatile building block for creating active pharmaceutical ingredients (APIs) and candidate molecules.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides requiring specific aryl-boronate intermediates.
• Material Science: Employed in the synthesis of organic electronic materials, such as those for OLEDs and organic semiconductors.
• Ligand and Catalyst Development: Acts as a precursor for creating novel ligands and organometallic catalysts.
• Chemical Biology & Probe Synthesis: Useful for labeling and modifying biomolecules in diagnostic and research applications.

Basic Information

Product Name	2-(3-Methoxy-5-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	365564-09-6
Molecular Formula	C14H21BO3
Molecular Weight	248.13 g/mol
Synonyms	(3-Methoxy-5-methylphenyl)boronic acid pinacol ester; 2-(3-Methoxy-5-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Methoxy-5-methylbenzeneboronic acid pinacol ester; (3-Methoxy-5-methylphenyl)BPin; Pinacol (3-methoxy-5-methylphenyl)boronate; 5-Methyl-3-methoxyphenylboronic acid pinacol ester; CAS 365564-09-6
EINECS	Contact for details

Quality Control

Our 2-(3-Methoxy-5-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and prevent hydrolysis.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.