Description

2-(3,5-Dimethoxy)-Phenyl-4,4,5,5-Tetramethyl-(1,3,2)-Dioxaborolane is a high-purity, advanced boronic ester building block essential for modern synthetic chemistry. This compound is a critical reagent in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for the synthesis of novel active ingredients and functional materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key arylboronic ester precursor for the palladium-catalyzed formation of carbon-carbon bonds, widely used in medicinal chemistry.
• Pharmaceutical Intermediate Synthesis: Enables the construction of complex, drug-like molecules containing the 3,5-dimethoxyphenyl moiety for potential therapeutic agents.
• Agrochemical Research & Development: Used in the synthesis of novel herbicides, fungicides, and insecticides that require specific aryl frameworks.
• Materials Science & OLED Development: Serves as a building block for creating organic semiconductors, light-emitting materials, and advanced polymers.
• Chemical Biology & Probe Development: Facilitates the synthesis of labeled compounds and molecular probes for biological target identification and study.
• Scale-up Process Chemistry: Suitable for optimization and transition from laboratory-scale research to pilot plant and commercial manufacturing.

Basic Information

Product Name	2-(3,5-Dimethoxy)-Phenyl-4,4,5,5-Tetramethyl-(1,3,2)-Dioxaborolane
CAS No.	365564-07-4
Molecular Formula	C14H21BO4
Molecular Weight	264.13 g/mol
Synonyms	(3,5-Dimethoxyphenyl)boronic acid pinacol ester; 2-(3,5-Dimethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3,5-Dimethoxyphenylboronic acid pinacol ester; Pinacol (3,5-dimethoxyphenyl)boronate; (3,5-Dimethoxyphenyl)pinacolborane; 3,5-Dimethoxyphenyl-Bpin; CAS 365564-07-4
EINECS	Contact for details

Quality Control

Our production of 2-(3,5-Dimethoxy)-Phenyl-4,4,5,5-Tetramethyl-(1,3,2)-Dioxaborolane adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR (1H, 13C, 11B), and GC analysis, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥98.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.