Description

1,5-Cyclohexadiene-1-Acetonitrile, 3,4-Dihydroxy-, (3R,4S)-Rel- (9Ci) is a high-purity, stereochemically defined chiral intermediate of significant interest in advanced organic synthesis. Its unique dihydroxy-substituted cyclohexadiene-acetonitrile structure makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical development teams for the synthesis of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral building block in the research and development of new therapeutic agents, particularly for complex, stereospecific molecules.
• Asymmetric Synthesis: Utilized as a sophisticated starting material or intermediate in catalytic asymmetric reactions to introduce specific stereocenters.
• Fine Chemical Production: Serves as a precursor in the multi-step synthesis of specialty chemicals, agrochemicals, and performance materials.
• Academic & Industrial R&D: Employed in methodological studies and process chemistry development for novel synthetic routes.
• Ligand and Catalyst Development: Potential use in the design and synthesis of novel chiral ligands or organocatalysts due to its functional group array.

Basic Information

Product Name	1,5-Cyclohexadiene-1-Acetonitrile, 3,4-Dihydroxy-, (3R,4S)-Rel- (9Ci)
CAS No.	365458-97-5
Molecular Formula	C9H11NO2
Molecular Weight	165.19 g/mol
Synonyms	(3R,4S)-rel-3,4-Dihydroxy-1,5-cyclohexadiene-1-acetonitrile; 3,4-Dihydroxy-1,5-cyclohexadiene-1-acetonitrile, (3R,4S)-rel-; 1,5-Cyclohexadiene-1-acetonitrile, 3,4-dihydroxy-, (3R,4S)-rel-; rel-(3R,4S)-3,4-Dihydroxy-1,5-cyclohexadiene-1-acetonitrile; 365458-97-5; (rel-3R,4S)-3,4-Dihydroxy-1,5-cyclohexadiene-1-acetonitrile
EINECS	Contact for details

Quality Control

Our production of 1,5-Cyclohexadiene-1-Acetonitrile, 3,4-Dihydroxy-, (3R,4S)-Rel- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity, critical for sensitive synthetic applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral purity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.