Description

1-Ethyl-4-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzyl)Piperazine is a high-value, advanced pharmaceutical intermediate featuring a piperazine core and a pinacol boronate ester functional group. This compound is critical for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern synthetic chemistry for constructing carbon-carbon bonds. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of new drug candidates, particularly in creating biaryl structures common in many active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the discovery and production of advanced herbicides, fungicides, and insecticides that require specific, complex aromatic frameworks.
• Material Science Research: Serves as a precursor in the development of organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and semiconductors, where precise molecular architecture is essential.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and tags for studying biological processes and target engagement.
• Academic & Contract Research: A vital reagent for universities and CROs (Contract Research Organizations) conducting cutting-edge synthetic methodology research and library synthesis for drug discovery programs.

Basic Information

Product Name	1-Ethyl-4-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzyl)Piperazine
CAS No.	364794-83-2
Molecular Formula	C19H31BN2O2
Molecular Weight	330.27 g/mol
Synonyms	1-Ethyl-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl]piperazine; 4-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl]-1-ethylpiperazine; 1-Ethyl-4-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methyl)piperazine; N-Ethyl-4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)piperazine; (4-(1-Ethylpiperazin-4-ylmethyl)phenyl)boronic acid pinacol ester; 364794-83-2; Boronic acid, B-[4-[(4-ethyl-1-piperazinyl)methyl]phenyl]-, pinacol ester
EINECS	Contact for details

Quality Control

Our 1-Ethyl-4-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzyl)Piperazine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical characterization using techniques including NMR (1H, 13C, 11B), HPLC, and mass spectrometry to confirm identity and purity. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring full traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.