Description

4-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzyl]Morpholine is a high-purity, advanced pharmaceutical intermediate and versatile building block in organic synthesis. This compound is valued for its stability and reactivity, making it a critical component in the development of complex molecules. It is primarily sought after by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for applications in cross-coupling reactions and drug discovery.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) via Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Research: Used in the development of novel pesticides and herbicides requiring specific boronic ester functionalities.
• Material Science: Serves as a precursor for organic electronic materials, including polymers and small molecules for OLEDs and OFETs.
• Chemical Synthesis: A versatile reagent for introducing the morpholine-substituted benzyl boronic ester moiety into complex molecular architectures.
• Life Science Research: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Catalyst & Ligand Development: Potential use in the design of novel ligands for transition metal catalysis.

Basic Information

Product Name	4-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzyl]Morpholine
CAS No.	364794-79-6
Molecular Formula	C17H26BNO3
Molecular Weight	303.21 g/mol
Synonyms	4-[(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methyl]morpholine; 2-[4-(Morpholin-4-ylmethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)morpholine; Morpholine, 4-[[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methyl]-; 4-(4-(Pinacolatoboron)benzyl)morpholine
EINECS	Contact for details

Quality Control

Our 4-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzyl]Morpholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.