Description

1,2-Bis((Pinacolato)Boryl)Ethane is a high-value organoboron reagent featuring two pinacol-protected boron centers on an ethane backbone. This compound is a versatile and stable building block critical for modern synthetic chemistry, enabling efficient carbon-carbon and carbon-heteroatom bond formation. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for applications such as Suzuki-Miyaura cross-coupling and the synthesis of complex organic molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a key bis-boronic ester reagent for constructing biaryl and conjugated systems in pharmaceutical intermediates.
• Organic Synthesis Building Block: Used in iterative synthesis for the sequential introduction of boron functional groups to create complex molecular architectures.
• Pharmaceutical Intermediate Manufacturing: Employed in the research and development of active pharmaceutical ingredients (APIs) requiring specific boron-containing motifs.
• Agrochemical Synthesis: Facilitates the creation of novel herbicides, fungicides, and insecticides through efficient coupling methodologies.
• Materials Science Research: Applied in the development of organic electronic materials, such as OLEDs and semiconductors, where precise molecular structure is essential.
• Chemical Biology & Medicinal Chemistry: Acts as a probe or intermediate in the synthesis of boron-based enzyme inhibitors and other bioactive compounds.

Basic Information

Product Name	1,2-Bis((Pinacolato)Boryl)Ethane
CAS No.	364634-18-4
Molecular Formula	C18H34B2O4
Molecular Weight	344.08 g/mol
Synonyms	1,2-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)ethane; Ethane-1,2-diylbis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane); 1,2-Bis(pinacolatoboryl)ethane; 1,2-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)ethane; Pinacol 1,2-Ethanediylbis(boronate); 1,2-Ethanediylbis(boronic acid) bis(pinacol) ester
EINECS	Contact for details

Quality Control

Our 1,2-Bis((Pinacolato)Boryl)Ethane is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific research or cGMP guidelines upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.