Description

tert-Butyl 4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenethylcarbamate is a high-purity, protected boronic ester derivative that serves as a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for small molecule therapeutics.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and insecticides with complex aromatic structures.
• Material Science Research: Used in the development of organic electronic materials, such as polymers and small molecules for OLEDs and semiconductors.
• Suzuki-Miyaura Cross-Coupling: A versatile reagent for palladium-catalyzed coupling reactions to form biaryl and other conjugated systems.
• Peptidomimetic & PROTAC Development: Serves as a protected intermediate for constructing sophisticated molecules like proteolysis-targeting chimeras (PROTACs).
• Chemical Biology Probes: Utilized in the synthesis of labeled compounds and probes for target identification and validation studies.

Basic Information

Item	Details
Product Name	tert-Butyl 4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenethylcarbamate
CAS No.	360792-43-4
Molecular Formula	C19H30BNO4
Molecular Weight	347.26 g/mol
Synonyms	Boc-4-Phenethylboronic Acid Pinacol Ester; N-Boc-2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethanamine; 2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethyl Carbamic Acid tert-Butyl Ester; tert-Butyl [2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]ethyl]carbamate; 4-(N-Boc-aminoethyl)phenylboronic Acid Pinacol Ester; 360792-43-4; Boc-Phe(4-Bpin)-OH pinacol ester (common abbreviation)
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenethylcarbamate is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality commitment ensures the material meets the stringent requirements for pharmaceutical R&D and scale-up.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label or COA. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and prevent decomposition. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Purity (HPLC, Area %)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.