Description

Carbamic Acid, [(1R)-1-(2S)-Oxiranylethyl]-, 1,1-Dimethylethyl Ester (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its core value lies in its dual functionality, incorporating both a protected carbamate group and an epoxide (oxirane) ring, making it a versatile precursor for constructing complex molecular architectures with precise stereochemistry. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs), chiral ligands, and other fine chemicals where stereochemical integrity is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the asymmetric synthesis of novel drug candidates, including protease inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Used in the development of enantiomerically pure pesticides and herbicides, where specific stereochemistry can enhance efficacy and reduce environmental impact.
• Chiral Auxiliary/ Ligand Precursor: Serves as a starting material for the preparation of chiral catalysts, auxiliaries, and resolving agents used in asymmetric catalysis.
• Peptidomimetics Research: The protected carbamate and epoxide functionalities are valuable for constructing peptide analogs and conformationally restricted scaffolds in medicinal chemistry.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for producing high-value, stereochemically complex specialty chemicals.

Basic Information

Product Name	Carbamic Acid, [(1R)-1-(2S)-Oxiranylethyl]-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	357385-69-4
Molecular Formula	C9H17NO3
Molecular Weight	187.24 g/mol
Synonyms	(2R,3S)-1-[(tert-Butoxycarbonyl)amino]-3,4-epoxybutane; tert-Butyl N-[(2R,3S)-3,4-epoxybutan-2-yl]carbamate; (2R,3S)-1-(Boc-amino)-3,4-epoxybutane; (2R,3S)-3,4-Epoxy-1-[(tert-butoxycarbonyl)amino]butane; Boc-(2R,3S)-3,4-epoxybutylamine; (2R,3S)-1-Amino-3,4-epoxybutane tert-butylcarbamate; (2R,3S)-1-(tert-Butoxycarbonylamino)-3,4-epoxybutane
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, [(1R)-1-(2S)-Oxiranylethyl]-, 1,1-Dimethylethyl Ester (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC to confirm enantiomeric/excess and standard identity and purity assays. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed when not in use to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.