Description

4-Methylbenzylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. Its primary value lies in its enhanced stability and solubility compared to the free boronic acid, making it a superior reagent for critical carbon-carbon bond-forming reactions. This compound is a vital building block for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for complex synthesis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing biaryl and other conjugated systems in pharmaceutical active ingredients and organic electronic materials.
• Pharmaceutical Intermediate Synthesis: Used in the research and production of drug candidates, particularly those containing substituted benzyl or tolyl motifs.
• Agrochemical Development: Serves as a building block for creating novel herbicides, fungicides, and insecticides with specific activity profiles.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands for transition metal catalysis and organoboron catalysts.
• Material Science Research: A precursor for organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Utilized in the development of activity-based probes and bioconjugation tools.

Basic Information

Item	Detail
Product Name	4-Methylbenzylboronic Acid Pinacol Ester
CAS No.	356570-52-0
Molecular Formula	C14H21BO2
Molecular Weight	232.13 g/mol
Synonyms	4-Methylbenzylboronic Acid Pinanediol Ester; (4-Methylbenzyl)boronic Acid Pinacol Ester; 2-(4-Methylbenzyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; p-Tolylmethylboronic Acid Pinacol Ester; Pinacol (4-Methylbenzyl)boronate; B-(4-Methylbenzyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-MethylbenzylBpin; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of our 4-Methylbenzylboronic Acid Pinacol Ester is produced and tested under a strict quality management system. We ensure the product meets the high-purity standards required for research and commercial synthesis. Comprehensive analytical testing, including NMR, HPLC, and GC, is performed to verify identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Purity (NMR)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.