Description

2-Oxetanecarboxylicacid,2-Methyl-4-Oxo-,Methylester,(2S)-(9Ci) CAS NO 353302-31-5 is a high-purity, chiral β-lactone derivative, a crucial advanced pharmaceutical intermediate (API) and building block in asymmetric synthesis. Its defined stereochemistry and reactive oxetanone core make it invaluable for constructing complex molecular architectures with high enantiomeric purity. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of protease inhibitors, antibiotics, and other bioactive molecules requiring specific stereocenters.
• Agrochemical Synthesis: Used in the research and production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Polymer Chemistry: Serves as a monomer or co-monomer for creating specialized polymers with tailored degradation profiles or functional groups.
• Organic Synthesis Building Block: Employed in ring-opening reactions, [2+2] cycloadditions, and other transformations to introduce the 2-methyl-4-oxo-oxetane moiety.
• Material Science Research: Investigated for developing novel materials with specific optical or mechanical properties derived from its strained ring system.
• Chemical Biology Probes: Utilized in the design and synthesis of activity-based probes for studying enzyme function and mechanism.

Basic Information

Product Name	2-Oxetanecarboxylicacid,2-Methyl-4-Oxo-,Methylester,(2S)-(9Ci)
CAS No.	353302-31-5
Molecular Formula	C6H8O4
Molecular Weight	144.13 g/mol
Synonyms	(2S)-2-Methyl-4-oxooxetane-2-carboxylic acid methyl ester; Methyl (2S)-2-methyl-4-oxooxetane-2-carboxylate; (S)-2-Methyl-4-oxo-oxetane-2-carboxylic acid methyl ester; 2-Oxetanecarboxylic acid, 2-methyl-4-oxo-, methyl ester, (2S)-; β-Lactone derivative; Chiral oxetanone ester; (S)-Methyl 2-methyl-4-oxooxetane-2-carboxylate
EINECS	Contact for details

Quality Control

Our production of 2-Oxetanecarboxylicacid,2-Methyl-4-Oxo-,Methylester,(2S)-(9Ci) adheres to stringent quality management systems, ensuring batch-to-batch consistency for critical R&D and manufacturing applications. We provide comprehensive analytical data, including chiral purity (enantiomeric excess) verification via chiral HPLC or GC, to meet the exacting standards of pharmaceutical development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Chiral Purity (Enantiomeric Excess)	≥ 98.0% ee (by Chiral HPLC/GC)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.