Description

(R)-(+)-2-(Fluorodiphenylmethyl)Pyrrolidine is a high-value, chiral pyrrolidine derivative featuring a fluorinated diphenylmethyl moiety, serving as a critical building block in asymmetric synthesis. This compound is essential for the development of novel active pharmaceutical ingredients (APIs) and advanced materials due to its ability to impart stereochemical control and unique physicochemical properties. It is primarily needed by research and development chemists, process development teams, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of enantiomerically pure drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Asymmetric Catalyst Ligand: Used as a precursor or component in the development of novel chiral ligands for transition metal catalysis.
• Agrochemical Synthesis: Employed in the research and production of advanced, stereoselective pesticides and herbicides.
• Material Science Research: Serves as a monomer or functional additive in the development of specialty polymers with tailored optical or electronic properties.
• Academic & Contract Research: A valuable reagent for methodological development in organic and medicinal chemistry within academic and CRO (Contract Research Organization) settings.

Basic Information

Product Name	(R)-(+)-2-(Fluorodiphenylmethyl)Pyrrolidine
CAS No.	352535-00-3
Molecular Formula	C17H18FN
Molecular Weight	255.33 g/mol
Synonyms	(R)-2-(Fluorodiphenylmethyl)pyrrolidine; (R)-(+)-α-Fluoro-α-phenylbenzenepropanamine, hexahydro-; (R)-α-(Fluorodiphenylmethyl)pyrrolidine; (R)-NSC 339242; (R)-2-[(Fluorodiphenyl)methyl]pyrrolidine; (R)-1-(Fluorodiphenylmethyl)-2-pyrrolidine; (R)-2-(Fluorodiphenylmethyl)-1-azacyclopentane
EINECS	Contact for details

Quality Control

Our (R)-(+)-2-(Fluorodiphenylmethyl)Pyrrolidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure it meets the high-purity standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.