Description

5-Chloro-2-Isopropoxyphenylboronic Acid is a high-purity organoboron compound that serves as a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biphenyl or substituted phenyl moieties.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific chlorinated biphenyl scaffolds.
• Material Science Research: Employed in the development of organic electronic materials, such as ligands for catalysts and monomers for functional polymers.
• Suzuki-Miyaura Cross-Coupling: A fundamental reagent for forming carbon-carbon bonds between aryl halides and this boronic acid, a cornerstone reaction in medicinal and process chemistry.
• Chemical Library Development: Utilized in high-throughput and combinatorial chemistry for creating diverse compound libraries for biological screening.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.

Basic Information

Product Name	5-Chloro-2-Isopropoxyphenylboronic Acid
CAS No.	352534-87-3
Molecular Formula	C9H12BClO3
Molecular Weight	214.45 g/mol
Synonyms	(5-Chloro-2-isopropoxyphenyl)boronic Acid; 2-Isopropoxy-5-chlorophenylboronic Acid; 5-Chloro-2-(1-methylethoxy)benzeneboronic Acid; Boronic acid, B-(5-chloro-2-isopropoxyphenyl)-; 5-Chloro-2-isopropoxybenzeneboronic Acid; CAS 352534-87-3
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Isopropoxyphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee it meets the stringent requirements for advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.