Description

Methyl 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate is a high-value organoboron reagent, specifically a boronic ester derivative. This compound is a critical building block in modern synthetic chemistry, enabling precise carbon-carbon bond formation. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of complex molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl structures found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific aromatic boronate motifs.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of organic electronic materials, such as polymers for OLEDs and OFETs.
• Chemical Biology & Medicinal Chemistry: Employed in the synthesis of probe molecules and drug candidates for target identification and structure-activity relationship (SAR) studies.
• Catalyst & Ligand Development: Acts as a starting material for synthesizing novel bidentate ligands and organometallic catalysts.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke fine chemicals and advanced intermediates on a commercial scale.

Basic Information

Product Name	Methyl 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate
CAS No.	352534-74-8
Molecular Formula	C14H19BO4
Molecular Weight	262.11 g/mol
Synonyms	3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid methyl ester; Methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate; 3-(Pinacolatoboryl)benzoic acid methyl ester; Methyl 3-(pinacolatoboryl)benzoate; Methyl m-(pinacolatoboryl)benzoate; 3-Methoxycarbonylphenylboronic acid pinacol ester; 3-Carbomethoxyphenylboronic acid pinacol ester; Benzoic acid, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are provided with every shipment. We support compliance with REACH and other relevant global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) for prolonged storage or when opening containers to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥98.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.