Description

2,5-Dichlorophenylzinc Iodide is a versatile organozinc reagent, specifically an arylzinc halide, widely used in modern synthetic organic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation through cross-coupling reactions, offering excellent functional group tolerance and selectivity. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity building blocks for complex molecule synthesis.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for the Negishi and other transition-metal-catalyzed cross-couplings to introduce the 2,5-dichlorophenyl moiety into drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Manufacturing: Used in the synthesis of herbicides, fungicides, and insecticides that incorporate dichlorinated aromatic structures for enhanced biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts used in asymmetric synthesis and polymerization processes.
• Material Science Research: Employed in the construction of organic electronic materials, such as OLEDs and semiconductors, where precise aromatic architecture is critical.
• Custom Chemical Synthesis: Provides a reliable and reactive handle for constructing complex, polyfunctional aromatic compounds in contract research and kilo-lab scale production.

Basic Information

Product Name	2,5-Dichlorophenylzinc Iodide
CAS No.	352530-43-9
Molecular Formula	C6H3Cl2ZnI
Molecular Weight	348.26 g/mol
Synonyms	(2,5-Dichlorophenyl)zinc Iodide; Zinc, (2,5-dichlorophenyl)iodo-; 2,5-Dichlorophenylzinc Iodide Solution; (2,5-Dichlorophenyl)iodozinc; Iodo(2,5-dichlorophenyl)zinc; Dichlorophenylzinc Iodide; Organozinc Reagent 352530-43-9
EINECS	Contact for details

Quality Control

Our 2,5-Dichlorophenylzinc Iodide is manufactured under strict quality protocols to ensure batch-to-batch consistency and high reactivity. Each lot is characterized by NMR (1H, 13C) and titration to confirm identity, concentration, and purity. We provide comprehensive Certificates of Analysis (COA) detailing all specifications. Our quality management system supports compliance with cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Due to its moisture-sensitive (hygroscopic) and easily oxidized nature, this reagent must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. For prolonged stability, storage at 2-8°C is recommended. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution (typically in THF)
Concentration	0.5 M in THF (or as specified)
Assay (Titration)	≥ 95%
Identification (NMR)	Conforms to structure
Water Content (KF)	≤ 500 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.