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Bis(Iodomethyl)Zinc CAS NO 14399-53-2
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CAS No.:14399-53-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Bis(Iodomethyl)Zinc is a highly reactive organozinc reagent, a valuable synthon for introducing the iodomethyl group in organic synthesis. Its primary value lies in its utility as a key building block for the formation of carbon-carbon bonds, particularly in Reformatsky-type reactions and cyclopropanation processes. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to construct complex molecular architectures.
Application
- Pharmaceutical Intermediate Synthesis: A critical reagent for constructing complex, chiral molecules in active pharmaceutical ingredient (API) development.
- Agrochemical Manufacturing: Used in the synthesis of novel pesticides and herbicides requiring specific cyclopropane or other ring structures.
- Organic Synthesis Reagent: Employed in Reformatsky reactions for the preparation of β-hydroxy esters and other valuable intermediates.
- Cyclopropanation Reactions: Serves as a source of a methylene unit for the efficient synthesis of cyclopropane rings, a common motif in bioactive compounds.
- Polymer & Materials Science: Used in the research and development of specialized polymers and functional materials.
- Cross-Coupling Reactions: Acts as an organometallic coupling partner in transition metal-catalyzed reactions to form new C-C bonds.
Basic Information
| Product Name | Bis(Iodomethyl)Zinc |
| CAS No. | 14399-53-2 |
| Molecular Formula | C2H4I2Zn |
| Molecular Weight | 323.25 g/mol |
| Synonyms | Diiodomethylzinc; Zinc, bis(iodomethyl)-; Iodomethylzinc iodide; (Iodomethyl)zinc iodide; Zinc di(iodomethanide); Zinc(II) bis(iodomethanide); Reformatsky Reagent Analog; Organozinc Reagent (Iodomethyl) |
| EINECS | Contact for details |
Quality Control
Our products undergo rigorous quality testing to ensure compliance with industry standards for research and industrial use. Each batch is characterized to confirm identity, purity, and reactivity profile. Certificates of Analysis (COA) detailing specific analytical results are available upon request to support your quality assurance protocols.
Storage
Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature and sensitivity to air and light, this material should be stored under an inert atmosphere (argon or nitrogen) at recommended temperatures between 2°C and 8°C. Handle and store away from strong bases and incompatible materials.
Specification
| Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow solution or solid* |
| Identification (NMR/IR) | Conforms to structure |
| Assay (Titration) | ≥ 90% (Typical in specified solvent) |
| Solvent (if supplied as solution) | Specified (e.g., Tetrahydrofuran, Diethyl ether) |
| Concentration (if supplied as solution) | 0.5M - 1.0M (Custom concentrations available) |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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