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2,4-Dichlorophenylzinc Iodide CAS NO 352530-42-8


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CAS No.:352530-42-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2,4-Dichlorophenylzinc Iodide is a highly reactive organozinc reagent, specifically an arylzinc halide, widely used in modern synthetic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation, particularly in cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require precise and reliable building blocks for developing active ingredients and functional molecules.

Application

  • Pharmaceutical Intermediate Synthesis: A key reagent for the Negishi cross-coupling reaction to introduce the 2,4-dichlorophenyl moiety into target molecules during the synthesis of active pharmaceutical ingredients (APIs).
  • Agrochemical Development: Used in the research and production of herbicides, fungicides, and insecticides where the dichlorophenyl group is a critical structural component.
  • Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands and organometallic catalysts used in asymmetric synthesis and other catalytic processes.
  • Material Science Research: Employed in the creation of novel organic electronic materials, such as those for OLEDs or conductive polymers, through controlled aryl-aryl coupling.
  • Fine Chemical Manufacturing: Facilitates the production of complex, high-value specialty chemicals where traditional methods are inefficient or lack selectivity.

Basic Information

Product Name 2,4-Dichlorophenylzinc Iodide
CAS No. 352530-42-8
Molecular Formula C6H3Cl2ZnI
Molecular Weight 348.26 g/mol
Synonyms Zinc, (2,4-dichlorophenyl)iodo-; (2,4-Dichlorophenyl)iodozinc; Iodo(2,4-dichlorophenyl)zinc; 2,4-Dichlorophenylzinc iodide solution; (2,4-Dichlorophenyl)zinc iodide; Organozinc reagent 352530-42-8
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Quality Control

Every batch of 2,4-Dichlorophenylzinc Iodide is manufactured and handled under strict quality protocols, typically supplied as a solution in tetrahydrofuran or other suitable solvents. Quality is assured through rigorous analytical testing, including titration for zinc content, GC or HPLC analysis for purity and solvent composition, and NMR for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. This material is hygroscopic (moisture-sensitive) and air-sensitive. For optimal stability, store under an inert atmosphere (argon or nitrogen) at 2-8°C. The solution form is typically stored in sealed, septum-capped bottles or Schlenk flasks to prevent exposure to moisture and oxygen, which can degrade the reagent.

Specification

Item Specification
Appearance (Solution) Colorless to pale yellow or brown solution
Concentration 0.5 M in THF (or as specified)
Assay (Titration) ≥ 95% (as C6H3Cl2ZnI)
Identification (NMR) Conforms to structure
Solvent Content (GC) Meets specified range

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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