Description

6-Methoxy-2-Pyridylzinc Bromide is a versatile organozinc reagent, specifically a pyridylzinc bromide derivative, widely used in modern synthetic organic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation, particularly in cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, reactive intermediates for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for introducing the 6-methoxy-2-pyridyl moiety into target molecules during the research and development of new drug candidates.
• Negishi Cross-Coupling Reactions: Used as a nucleophilic coupling partner with various aryl, heteroaryl, or vinyl halides/pseudohalides to form biaryl and heterobiaryl structures.
• Agrochemical Active Ingredient Production: Employed in the synthesis of complex molecules for crop protection agents and herbicides.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized pyridine-containing ligands used in catalysis.
• Material Science Research: Facilitates the creation of organic electronic materials and metal-organic frameworks (MOFs) with tailored properties.
• Fine Chemical and Specialty Chemical Manufacturing: Applied in the custom synthesis of high-value, complex organic compounds for various industrial applications.

Basic Information

Product Name	6-Methoxy-2-Pyridylzinc Bromide
CAS No.	352530-39-3
Molecular Formula	C6H7BrNOMgZn (commonly represented in solution as (6-MeO-2-Py)ZnBr)
Molecular Weight	Contact for details
Synonyms	(6-Methoxypyridin-2-yl)zinc bromide; 2-(6-Methoxypyridyl)zinc bromide; 6-Methoxy-2-pyridinezinc bromide; Zinc, bromo(6-methoxy-2-pyridinyl)-; (6-MeO-2-Py)ZnBr; 6-Methoxy-2-pyridylzinc bromide solution; 2-Pyridylzinc bromide, 6-methoxy-; Bromo(6-methoxy-2-pyridinyl)zinc
EINECS	Contact for details

Quality Control

Our 6-Methoxy-2-Pyridylzinc Bromide is manufactured under strict quality protocols to ensure batch-to-batch consistency and high reactivity. Each lot undergoes rigorous analytical testing, including titration for zinc content and GC/HPLC analysis for purity and solvent composition. Certificates of Analysis (COA) detailing concentration, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. This product is moisture-sensitive (hygroscopic) and should be stored under an inert atmosphere (argon or nitrogen) at recommended temperatures, typically between 2°C and 8°C for solutions or as specified. Keep away from strong acids and oxidizing agents. Use in a well-ventilated area.

Specification

Item	Specification
Appearance (Solution)	Colorless to pale yellow solution
Concentration	Typically 0.5 M in THF or as specified
Assay (Titration)	≥ 95%
Identification (IR/NMR)	Conforms to structure
Purity (GC/HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.