Description

6-Ethoxy-2-Naphthaleneboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its primary value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly in the development of active pharmaceutical ingredients (APIs), liquid crystal materials, and organic light-emitting diodes (OLEDs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides requiring specific biaryl scaffolds.
• Material Science: Serves as a monomer or building block for creating organic semiconductors, liquid crystals, and polymers for electronic applications.
• OLED Development: Employed in the synthesis of complex organic molecules used as emissive or charge-transport layers in organic light-emitting diodes.
• Chemical Research: A valuable reagent in academic and industrial R&D for methodology development and constructing molecular libraries.
• Catalyst Ligand Synthesis: Can be utilized to prepare sophisticated ligands for transition metal catalysis.

Basic Information

Product Name	6-Ethoxy-2-Naphthaleneboronic Acid
CAS No.	352525-98-5
Molecular Formula	C₁₂H₁₃BO₃
Molecular Weight	216.04 g/mol
Synonyms	2-(6-Ethoxynaphthalen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (Pinacol Ester); 6-Ethoxy-2-naphthylboronic Acid; (6-Ethoxy-2-naphthyl)boronic Acid; 2-Borono-6-ethoxynaphthalene; B-(6-Ethoxy-2-naphthalenyl)boronic Acid; 352525-98-5; 6-Ethoxy-2-Naphthaleneboronic Acid Pinacol Ester (common precursor).
EINECS	Contact for details

Quality Control

Our 6-Ethoxy-2-Naphthaleneboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive cross-coupling applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, moisture content, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.