Description

3-Methoxy-(2R)-(+)-Methyl-3-Oxopropylzinc Bromide is a high-value, chiral organozinc reagent essential for advanced asymmetric synthesis. This compound matters for its role as a key building block in the stereoselective formation of carbon-carbon bonds, enabling the production of complex, optically active molecules. It is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for developing new active ingredients and novel materials.

Application

• Asymmetric Synthesis: A crucial reagent for enantioselective additions in the synthesis of chiral pharmaceutical intermediates.
• Pharmaceutical R&D: Used in the construction of complex molecular scaffolds for new drug candidates, particularly in medicinal chemistry.
• Natural Product Synthesis: Facilitates the stereocontrolled synthesis of complex natural products and their analogs.
• Agrochemical Development: Employed in creating chiral active ingredients for herbicides, fungicides, and pesticides with improved efficacy.
• Material Science: Serves as a precursor for the development of specialized polymers and advanced organic materials.
• Process Chemistry: Used in scaling up synthetic routes from laboratory to pilot plant and commercial production.

Basic Information

Product Name	3-Methoxy-(2R)-(+)-Methyl-3-Oxopropylzinc Bromide
CAS No.	352525-75-8
Molecular Formula	C8H15BrO2Zn
Molecular Weight	288.50 g/mol
Synonyms	(2R)-3-Methoxy-2-methyl-3-oxopropylzinc bromide; (R)-3-Methoxy-2-methyl-3-oxo-1-propylzinc bromide; (+)-3-Methoxy-2-methyl-3-oxopropylzinc bromide; Zinc, bromo(3-methoxy-2-methyl-3-oxopropyl)-, (R)-; (R)-3-Methoxy-2-methyl-3-oxopropylzinc bromide solution; Chiral 3-oxopropylzinc bromide reagent; Organozinc reagent 352525-75-8
EINECS	Contact for details

Quality Control

Every batch of our 3-Methoxy-(2R)-(+)-Methyl-3-Oxopropylzinc Bromide is produced and tested under stringent quality management systems. We ensure high chiral purity and chemical consistency through advanced analytical techniques including NMR, HPLC, and titration methods. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and solution concentration are provided with each shipment to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. This material is hygroscopic (moisture-sensitive) and should be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. For optimal stability, maintain storage temperatures between 2°C and 8°C. Keep away from incompatible materials such as strong acids, oxidizing agents, and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Identification (NMR)	Conforms to structure
Assay (Titration)	0.5 M in THF (or as specified)
Enantiomeric Excess (HPLC)	≥ 98% ee
Purity (NMR/HPLC)	≥ 95%
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.