Description

4-Bromobenzylzinc Chloride 0.5M Solution is a versatile organozinc reagent, widely used as a key building block in modern synthetic chemistry. This solution offers a convenient and reactive source of the 4-bromobenzyl anion equivalent, enabling efficient carbon-carbon bond formation under mild conditions. It is an essential intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, facilitating the synthesis of complex organic molecules.

Application

• Pharmaceutical Intermediate Synthesis: A crucial reagent for constructing aryl-alkyl linkages in active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Manufacturing: Used in the production of advanced pesticides and herbicides, particularly for introducing substituted benzyl groups.
• Cross-Coupling Reactions: Serves as a nucleophilic partner in Negishi and related cross-coupling reactions with various electrophiles.
• Ligand and Material Science: Employed in the synthesis of specialized ligands for catalysis and novel organic materials.
• Academic & R&D Laboratories: A valuable tool for methodological development and exploring new synthetic pathways in organic chemistry.
• Fine Chemical Production: Key for the custom synthesis of complex, high-value specialty chemicals and flavors/fragrances intermediates.

Basic Information

Product Name	4-Bromobenzylzinc Chloride 0.5M Solution
CAS No.	352525-64-5
Molecular Formula	C7H6BrClZn
Molecular Weight	260.87 g/mol
Synonyms	(4-Bromobenzyl)zinc chloride solution; Zinc, chlorobromobenzyl-; 4-Bromobenzylzinc chloride; (4-Bromophenylmethyl)zinc chloride; Bromobenzylzinc chloride; 0.5M 4-Bromobenzylzinc Chloride in THF; Organozinc reagent 352525-64-5
EINECS	Contact for details

Quality Control

Our 4-Bromobenzylzinc Chloride 0.5M Solution is produced under stringent quality control protocols to ensure batch-to-batch consistency and reliability for critical synthetic applications. Each lot undergoes comprehensive analysis, including titration for precise molarity determination and impurity profiling. A Certificate of Analysis (COA) detailing purity, concentration, and solvent specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry, well-ventilated area. Keep away from heat, sparks, and open flame. Due to its highly volatile and easily oxidized nature, the container must be kept sealed and handled under inert conditions to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Concentration	0.5 M in THF
Assay (Titration)	≥ 0.45 M
Solvent	Tetrahydrofuran (THF)
Water Content (KF)	< 0.05%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.