Description

1-(3'-Trifluoromethylbiphenyl-3-Yl)Ethanone CAS NO 352032-25-8 is a high-purity, specialized organic compound featuring a biphenyl core substituted with a trifluoromethyl group and an acetyl moiety. This molecular architecture makes it a valuable and versatile advanced pharmaceutical intermediate and key building block in modern synthetic chemistry. It is primarily utilized by research institutions and industrial manufacturers engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in therapeutic areas requiring fluorinated compounds for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a key building block for developing advanced pesticides and herbicides, where the trifluoromethyl group can improve efficacy and environmental profile.
• Material Science Research: Used in the development of organic electronic materials, such as semiconductors and light-emitting diodes (OLEDs), due to its conjugated biphenyl system.
• Ligand and Catalyst Development: Employed in organometallic chemistry for creating specialized ligands that modify catalyst properties in asymmetric synthesis.
• Fluorine Chemistry Studies: An important compound for academic and industrial research focused on the introduction and behavior of fluorine atoms in complex organic molecules.
• Custom Synthesis and Scale-up: Provided for contract research organizations (CROs) and chemical companies requiring reliable, high-quality starting materials for custom synthesis projects.

Basic Information

Item	Details
Product Name	1-(3'-Trifluoromethylbiphenyl-3-Yl)Ethanone
CAS No.	352032-25-8
Molecular Formula	C15H11F3O
Molecular Weight	264.24 g/mol
Synonyms	3'-Trifluoromethyl-3-acetylbiphenyl; 1-[3'-(Trifluoromethyl)[1,1'-biphenyl]-3-yl]ethanone; 3-Acetyl-3'-trifluoromethylbiphenyl; 3'-Trifluoromethylbiphenyl-3-yl methyl ketone; 3-Acetyl-3'-(trifluoromethyl)biphenyl; [1,1'-Biphenyl]-3-ethanone, 3'-(trifluoromethyl)-; Ethanone, 1-[3'-(trifluoromethyl)[1,1'-biphenyl]-3-yl]-
EINECS	Contact for details

Quality Control

Our production of 1-(3'-Trifluoromethylbiphenyl-3-Yl)Ethanone adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality system is designed to support cGMP requirements for pharmaceutical intermediates, ensuring traceability and documentation excellence.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.