Description

3-Methoxy-2-Methylphenylboronic Acid Pinacol Ester is a high-purity, organoboron building block essential for modern synthetic chemistry. This compound matters as a key intermediate in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for developing new active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical reagent for forming carbon-carbon bonds between aryl halides and this boronic ester derivative.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of novel drug candidates, particularly those containing substituted biphenyl or heterobiaryl motifs.
• Agrochemical Active Ingredient Production: Serves as a building block for creating new herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for metal catalysis and organometallic complexes.
• Advanced Material Precursors: Useful in the creation of organic electronic materials, such as those for OLEDs or conductive polymers.
• Chemical Biology & Probe Synthesis: Facilitates the labeling and modification of biomolecules for diagnostic and research tools.

Basic Information

Product Name	3-Methoxy-2-Methylphenylboronic Acid Pinacol Ester
CAS No.	351456-69-4
Molecular Formula	C14H21BO3
Molecular Weight	248.13 g/mol
Synonyms	2-Methyl-3-methoxyphenylboronic acid pinacol ester; (3-Methoxy-2-methylphenyl)boronic acid pinacol ester; 2-Methyl-3-methoxybenzeneboronic acid pinacol ester; 3-Methoxy-2-methylbenzeneboronic acid pinacol ester; Pinacol (3-methoxy-2-methylphenyl)boronate; Boronic acid, B-(3-methoxy-2-methylphenyl)-, 1,1-dimethylethyl ester (9CI); CAS 351456-69-4
EINECS	Contact for details

Quality Control

Every batch of our 3-Methoxy-2-Methylphenylboronic Acid Pinacol Ester undergoes rigorous analytical testing to ensure it meets the high-purity standards required for sensitive synthetic applications. Our quality assurance protocols include NMR (¹H, ¹³C, ¹¹B), HPLC, and GC analysis to verify identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) documenting all test results is provided with each shipment to guarantee traceability and batch-to-batch consistency for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.