Description

Benzyl 2-(Benzyloxy)-4-Fluorobenzoate is a high-purity fluorinated aromatic ester building block of significant interest in advanced organic synthesis. This compound matters for its role as a key protected intermediate in the development of complex molecules, particularly in pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of novel drug candidates, particularly those containing fluorinated aromatic systems.
• Agrochemical Research: Used in the development of advanced herbicides, fungicides, and pesticides where the fluorobenzoate moiety can enhance biological activity and stability.
• Liquid Crystal & OLED Material Synthesis: Serves as a precursor for fluorinated aromatic components in electronic and display materials.
• Polymer Chemistry: Can be utilized to introduce fluorinated aromatic esters into specialty polymer chains, modifying their physical and chemical properties.
• Organic Synthesis Reagent: Acts as a protected carboxylic acid derivative in complex organic transformations, including cross-coupling reactions.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Benzyl 2-(Benzyloxy)-4-Fluorobenzoate
CAS No.	351445-97-1
Molecular Formula	C21H17FO3
Molecular Weight	336.36 g/mol
Synonyms	4-Fluoro-2-(phenylmethoxy)benzoic Acid Phenylmethyl Ester; Benzoic acid, 2-(benzyloxy)-4-fluoro-, benzyl ester; Benzyl 2-Benzyloxy-4-fluorobenzoate; 2-Benzyloxy-4-fluorobenzoic Acid Benzyl Ester; BBFB; 351445-97-1; Benzyl O-benzyl-4-fluorosalicylate
EINECS	Contact for details

Quality Control

Our Benzyl 2-(Benzyloxy)-4-Fluorobenzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.