Description

Benzaldehyde, 2-Bromo-5-[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]- is a high-value, protected synthetic intermediate designed for advanced organic synthesis. This compound matters because it provides a strategically functionalized benzaldehyde derivative, where the silyl ether group offers crucial protection for the phenolic hydroxyl during multi-step reactions, enabling precise molecular construction. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for building complex aromatic target molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing complex brominated and oxygenated aromatic systems.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Intermediate in the development of organic semiconductors, liquid crystals, and photoresist polymers.
• Fine Chemical Production: Employed in the custom synthesis of dyes, flavors, and fragrances requiring specific bromo- and alkoxy-substituted benzaldehyde motifs.
• Academic & Institutional R&D: A valuable reagent for methodological studies in organic chemistry, including cross-coupling and protection/deprotection strategies.

Basic Information

Product Name	Benzaldehyde, 2-Bromo-5-[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]-
CAS No.	351418-50-3
Molecular Formula	C₁₃H₁₉BrO₂Si
Molecular Weight	315.28 g/mol
Synonyms	2-Bromo-5-[(tert-Butyldimethylsilyl)oxy]benzaldehyde; 5-[(tert-Butyldimethylsilyl)oxy]-2-bromobenzaldehyde; 2-Bromo-5-((tert-butyldimethylsilyl)oxy)benzaldehyde; 2-Bromo-5-(TBDMSO)benzaldehyde; 2-Br-5-TBDMS-O-Benzaldehyde; Benzaldehyde, 2-bromo-5-[(1,1-dimethylethyl)dimethylsilyl]oxy]-; 2-Bromo-5-hydroxybenzaldehyde TBDMS ether
EINECS	Contact for details

Quality Control

Our Benzaldehyde, 2-Bromo-5-[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH Q7 guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.