Description

5-Fluoro-2-Methoxynicotinaldehyde is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both aldehyde and methoxy substituents on a fluorinated pyridine ring, makes it indispensable for constructing complex molecules with tailored properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluoronicotinaldehyde scaffold.
• Ligand and Catalyst Synthesis: Employed in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions and asymmetric synthesis.
• Material Science Precursor: Acts as a starting material for the synthesis of functionalized organic molecules used in electronic materials and liquid crystals.
• Chemical Biology Probes: Utilized to create fluorescent tags or molecular probes for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific fluorinated heterocycles.

Basic Information

Item	Details
Product Name	5-Fluoro-2-Methoxynicotinaldehyde
CAS No.	351410-62-3
Molecular Formula	C7H6FNO2
Molecular Weight	155.13 g/mol
Synonyms	5-Fluoro-2-methoxypyridine-3-carbaldehyde; 3-Formyl-5-fluoro-2-methoxypyridine; 5-Fluoro-2-methoxy-3-pyridinecarboxaldehyde; 2-Methoxy-5-fluoronicotinaldehyde; 5-Fluoro-2-methoxynicotinaldehyde; 351410-62-3; 5-Fluoro-2-methoxy-3-pyridinecarbaldehyde
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Methoxynicotinaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your internal specifications and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or after opening. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.