Description

1-Azetidinecarboxaldehyde, 2,4-Bis(Hydroxymethyl)-, (2S,4S)- (9Ci) CAS NO 351075-56-4 is a high-purity, stereochemically defined azetidine derivative, serving as a critical chiral building block in advanced organic synthesis. Its value lies in its unique bicyclic structure with dual hydroxymethyl groups, enabling precise molecular construction for complex target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients with specific three-dimensional architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, including protease inhibitors and other biologically active molecules.
• Agrochemical Research: Used in developing advanced pesticides and herbicides where specific stereochemistry is crucial for activity and selectivity.
• Ligand and Catalyst Development: Serves as a precursor for creating sophisticated chiral ligands used in asymmetric catalysis.
• Peptidomimetics: Integral for constructing conformationally restricted peptide analogs in medicinal chemistry programs.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes to study enzyme function and biological pathways.
• Material Science: Potential monomer or cross-linker for specialty polymers requiring rigid, functionalized building blocks.

Basic Information

Product Name	1-Azetidinecarboxaldehyde, 2,4-Bis(Hydroxymethyl)-, (2S,4S)- (9Ci)
CAS No.	351075-56-4
Molecular Formula	C7H13NO3
Molecular Weight	159.18 g/mol
Synonyms	(2S,4S)-2,4-Bis(hydroxymethyl)azetidine-1-carbaldehyde; (2S,4S)-1-Formyl-2,4-bis(hydroxymethyl)azetidine; (2S,4S)-Azetidine-1-carboxaldehyde, 2,4-bis(hydroxymethyl)-; 2,4-Bis(hydroxymethyl)azetidine-1-carboxaldehyde (S,S-isomer); (S,S)-1-Azetidinecarboxaldehyde, 2,4-bis(hydroxymethyl)-; 351075-56-4; (2S,4S)-1-Carbamoyl-2,4-bis(hydroxymethyl)azetidine (related aldehyde)
EINECS	Contact for details

Quality Control

Our 1-Azetidinecarboxaldehyde, 2,4-Bis(Hydroxymethyl)-, (2S,4S)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting research and development standards. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a dry, cool environment. Due to its hygroscopic and easily oxidized nature, prolonged exposure to air, moisture, or elevated temperatures should be strictly avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.